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Spotted Fever Rickettsiosis

Spotted fever rickettsiosis (SFR) is a group of tick-borne diseases caused by closely related Rickettsia bacteria, including Rickettsia rickettsii and Rickettsia parkeri. These bacteria are primarily spread to humans through the bite of infected ticks such as the American dog (wood) tick and the Gulf Coast tick. The most serious reported spotted fever in the United States is Rocky Mountain spotted fever (RMSF). After a tick bite, the bacteria enter the human body and infect the cells lining blood vessels, leading to widespread inflammation and damage. The signs and symptoms of SFR can vary depending on the specific bacteria and individual factors, such as the person's immune response. In Alabama, most cases occur between March and October when tick activity is highest.

Frequently Asked Questions (FAQs)

Symptoms of Rocky Mountain spotted fever (RMSF) can include the onset of fever, headache, muscle pain, chills, and a rash that can begin 3-12 days after an infected tick bite. The RMSF rash can vary in appearance but usually begins on the ankles and wrists and spreads to the rest of the body, including the trunk, and sometimes to the soles of the feet and the palms of the hands. If left untreated, RMSF can be fatal. Rickettsia parkeri rickettsiosis symptoms typically appear 2-10 days after a tick bite and are usually less severe. Its symptoms include fever, headache, muscle aches, a rash, and an eschar (dry, dark scab). People with Rickettsia parkeri rickettsiosis usually have a rash with widely separated spots and typically develop an eschar at the site of the tick bite. The eschar starts as a pus-filled pimple and then ruptures and scabs over.

Common signs and symptoms:

  • Fever
  • Headache
  • Rash (usually appears 2 - 4 days after fever begins)
  • Eschar (dry, dark scab)
  • Nausea and/or vomiting
  • Stomach pain
  • Muscle pain
  • Lack of appetite

Long-term health problems (Typically associated with RMSF):

  • Swelling of the brain leading to behavioral changes and coma
  • Multiorgan system damage, including
    • Damage to blood vessels requiring amputation of arms, legs, fingers, or toes
    • Difficulty breathing due to lung damage
    • Kidney failure
  • Paralysis
  • Hearing loss

It's important to note that the severity and combination of symptoms can vary. Some individuals may experience mild symptoms, while others may develop more severe manifestations.

If you suspect you have been exposed to ticks or are experiencing symptoms consistent with Spotted Fever Rickettsiosis, including Rocky Mountain Spotted Fever, seek medical attention promptly. Early diagnosis and treatment with appropriate antibiotics, such as doxycycline, can help reduce symptom severity and prevent complications.

SFR is primarily transmitted through the bite of infected ticks. These ticks act as the main vectors, passing bacteria to humans during feeding.

When an infected tick bites a person, bacteria in its saliva enter the bloodstream. The bacteria infect cells lining blood vessels, causing inflammation and potentially damaging organs and tissues.

Ticks become infected by feeding on animals such as small mammals, allowing the bacteria to persist in their bodies. Different tick species may transmit disease depending on the region. Person-to-person transmission is extremely rare.

Anyone who spends time outdoors in Alabama is at risk of contracting SFR, because the ticks that spread this disease are most often found in wooded, brushy areas. People engaged in outdoor occupations, such as farmers and landscapers, may be at increased risk of being bitten by an infected tick, as are people who regularly hike, camp, hunt, or garden in or around wooded areas.

Ticks may also dwell in the property surrounding Alabama homes, especially if your yard is either next to a brushy area or has tall grass and/or leaf litter. Even outside our state's forests, it is important to take the necessary steps to prevent tick bites in any environment where these ticks live.

Prevention begins with you! Limiting exposure to ticks is the most effective method of prevention of tick-transmitted diseases. For persons exposed to tick-infested habitats, prompt, careful inspection and removal of crawling or attached ticks is an important way to prevent disease. It may take several hours of attachment before the organisms are transmitted from the tick to the host. Here are some key preventive steps you can take:

  • Avoid Tick-Infested Areas
  • Wear Protective Clothing
  • Use Insect Repellents
  • Conduct Tick Checks
  • Create a Tick-Safe Environment
  • Protect Pets
  • Educate Yourself
  • Stay Informed

It is important to note that the severity and combination of symptoms can vary. Some individuals may experience mild symptoms, while others may develop more severe manifestations. In severe cases, SFR can lead to complications affecting multiple organs, such as the heart, lungs, kidneys, and central nervous system.

If you suspect you have been exposed to ticks or are experiencing symptoms consistent with SFR, seek medical attention promptly. Early diagnosis and treatment with appropriate antibiotics, such as doxycycline, can help reduce symptom severity and prevent complications.

Early recognition and treatment of SFR is crucial to prevent complications. If you suspect you have been exposed to ticks or are experiencing symptoms consistent with the disease, seek medical attention promptly. The healthcare provider will evaluate your symptoms, order appropriate tests, and initiate treatment based on clinical judgment and the epidemiological context. Some cases of spotted fever are not life-threatening and can resolve over time, even without treatment. For others, especially RMSF, early treatment with the antibiotic doxycycline can be lifesaving.

Doxycycline is the recommended antibiotic treatment for all spotted fevers, including RMSF, in adults and children of all ages.

Education Materials

Additional Resources

Information for Provider and Public Health Professionals

The Alabama Department of Public Health tracks and monitors cases of tick-borne diseases, including Spotted Fever Rickettsiosis, through passive surveillance systems, which rely on healthcare providers to submit laboratory results and medical records for review. Below is a list of resources for health care providers and public health professionals.





Page last updated: June 10, 2026